Water treatment plant operators need knowledge in the following areas:
- Chemistry: The properties of substances and the changes that occur when they interact.
 - Biology: Cells, plants, and animals and how they function.
 - Mechanical: The design, use, and repair of machines and tools.
 - Mathematics: The rules and uses of numbers.
 - Public Safety and Security: How to protect people and property.
 - Production and Processing: How products are made and distributed.
 - Engineering and Technology: How to use computers and rules of engineering to design and produce goods and services.
 - Administration and Management: How to run a business or group.
 - Computers and Electronics: Computer hardware and software.
 - Education and Training: The methods of teaching and learning.
 - Clerical: General office work such as filling and storing information.
 - English Language: The meaning and use of the English language.
 - Customer and Personal Service: Providing special services to customers based on their needs.