If you want to work in a classroom, helping students with learning activities, you should take courses in a variety of subjects, especially the ones in which you'd like to assist.

Bilingual teaching assistants, especially those who speak Spanish, are in great demand. You may want to supplement your course work with courses in Spanish or another second language.

Some states have established guidelines and requirements for teaching assistants. Many of these states require some college course work as well as supervised practice-teacher assisting experience. If the program you choose does not require a practicum, you should seek one out anyway. It doesn't only fulfill possible state teacher assisting requirements. It also gives you valuable hands-on experience and the chance to work with a potential reference or even employer.